Maternal age, maternal education, husband's education, knowledge about anemia and iron folic acid was found to be significantly associated with adherence to IFAS. This study showed that compliance to IFAS was low. Factors significantly associated with compliance to IFAS were maternal age ≥ 25 years, maternal education, husband's education, knowledge of anemia, and knowledge of IFA. The prevalence of compliance to IFAS was (177, 44.3%). Results were reported as crude and adjusted odds ratios with 95% confidence intervals. P values less than 0.05 were considered significant. The variables with p-value < 0.25 in the bivariable analysis were entered into the multivariable logistic regression model. Data were entered into Epi-info and exported to Statistical Package for Social Sciences for analysis. Pre-tested structured questionnaire was used to collect data through face to face interview. Pregnant women were selected through systematic random sampling. A facility-based cross-sectional study was conducted among 400 pregnant women. The study aimed to assess compliance with IFAS and its associated factors among antenatal care (ANC) attendees in Wondo District, Southern Ethiopia. Despite high coverage of iron and folic acid supplementation (IFAS), low compliance is reported. Pregnant women are at high risk for iron deficiency anemia due to increased nutrient requirements during pregnancy.
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